June 13, 2014

A flexible antibody purification process based on ReadyToProcess™ products



In the biopharmaceutical industry, the need to reduce cost while increasing the success rate of drug development requires effective screening tools to produce robust and high yield purification processes. In this work, we describe the scaling up of a two-step antibody purification process (described in GE Healthcare application notes 28-9468-58 and 28-9509-60) using ReadyToProcess products to achieve shorter time-to-clinic and cost savings. 

The results from the scaled-up process using the ReadyToProcess platform were compared with those from the scaled-up process using the AxiChrom™ column format.

Tags: Single-use; antibody purification; ready-to-process; polishing; MAb Select; Capto