December 2, 2022

Designing a 1.5 L Bench-Scale Model of a Perfusion Process

Establishing an appropriate model allows for higher throughput during simultaneous operation and monitoring of several cultures at different process conditions. In this article, we discuss the development of a bench-scale (1.5 L working volume) proof of concept model for a 50 L Xcellerex™ XDR-50 bioreactor and Xcellerex™ APS perfusion system with comparable growth, volumetric productivity, and product quality.


Tags: hyclone, Xcellerex, Cell culture; perfusion