July 2, 2018

Developing an Efficient Adenovirus Downstream Purification Process

adenovirusAdenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and adenovirus is evaluated as vaccine delivery system in many preclinical and clinical studies of various infectious diseases. Adenovirus is also explored as a potential viral vector for gene therapy and as an oncolytic virus. This application note describes the development of downstream chromatography steps for purification of adenovirus from HEK293 cell culture harvest.

To read the application note click here.

Tags: vaccines, chromatography, downstream, adenovirus, viral vector