November 28, 2016

Efficient Purification of the Pertussis Antigens Toxin, Filamentous Haemagglutinin, and Pertactin in Chromatography Workflows

This application note describes the purification of pertussis toxin (PT), filamentous haemagglutinin (FHA), and pertactin (PRN) in a process based on modern chromatography resins. The described method resulted in higher purity and yield than what can be expected from a purification process based on salt precipitations and sucrose gradient centrifugation.

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Tags: vaccines, chromatography, filamentous, pertussis