March 13, 2018

Evaluation of Performance of a Disposable mAb Affinity Chromatography Column Used Over Multiple Process Cycles

Disposable mAb Affinity Chromatography ColumnPresanitized and prequalified disposable chromatography columns are widely used to save time in downstream processes. However, reuse of such columns could positively impact process economy. This application note demonstrates cycling of ReadyToProcess™ MabSelect SuRe™ LX columns in multiple process runs. Analysis of mAb purity and recovery as well as column bed integrity testing show that the column can be used with maintained performance for at least 50 cycles, providing significant process economic benefits.

Read more in this application note.

Tags: multiple process cycles bioprocess, re-cycling columns, prepacked columns