September 22, 2022

FAQ: Scale-up and scale-down with mechanistic modeling




A mechanistic model can simplify your process development projects. The model eases scale-up and scale-down between lab scale and production scale. To apply model-based scale-up and scale-down in a straightforward manner, you must know the scale-dependency of the underlying effects, choose the correct scale for model calibration, and understand how scale-up integrates into a mechanistic modeling workflow.

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Tags: mechanistic modeling, chromatography, downstream, process development