November 4, 2021

Fc Receptor Binding Assays Using Surface Plasmon Resonance

Fc receptors and antibodies contribute to the control of both inflammatory and anti-inflammatory responses of the innate immune system. Fc receptor binding are important for the safety and efficacy of a biopharmaceutical drug and monitoring of Fc receptor binding is crucial. This document describes how to set up, run, and evaluate Fcγ receptor assays on Biacore™ systems in order to establish standardized guidelines.

Tags: Surface plasmon resonance; Biacore; Fcgamma; receptor analysis