This application note describes the performance of the XDR‑500 MO fermentor system in comparison with the XDR‑50 MO fermentor. Domain antibody production in E. coli was used as the model process. Fermentations were performed as fed‑batch processes, with glycerol feed and a two‑stage induction strategy. The presented data was collected as foundational single‑use fermentation work, and can be used when scaling between the XDR‑50 MO and XDR‑500 MO systems.
November 30, 2017
Performance of Single-Use Xcellerex™ XDR‑500 MO and XDR‑50 MO Stirred-Tank Fermentor Systems
This application note describes the performance of the XDR‑500 MO fermentor system in comparison with the XDR‑50 MO fermentor. Domain antibody production in E. coli was used as the model process. Fermentations were performed as fed‑batch processes, with glycerol feed and a two‑stage induction strategy. The presented data was collected as foundational single‑use fermentation work, and can be used when scaling between the XDR‑50 MO and XDR‑500 MO systems.