October 11, 2018

Process Economy Simulations on a Protein A Capture Step

protein A chromatography resinMabSelect PrismA is a next‐generation protein A chromatography resin that offers significantly enhanced alkaline stability and capacity compared with its predecessor products. This application note gives calculation examples that highlight scenarios where the enhanced capacity and alkaline‐stability of MabSelect PrismA can provide process economic benefits to large‐scale mAb processing. Calculations show that normalized cost per batch can be reduced by 75% using MabSelect PrismA compared with the predecessor MabSelect SuReTM resin.

Tags: Mab, Protein A resin, chromatography, process economy, MabSelect PrismA