July 30, 2020

Production of Recombinant Adeno-associated Virus Vectors Using Microcarrier Culture of HEK293T Cells

As of March 2020, more than 4310 gene therapy clinical trials have been performed worldwide, with only 518 of them in Phase III and Phase IV. As the gene therapy projects enter clinical Phase III or get market approval, large-scale production of viruses has become a limiting factor in the industrialization of gene therapy.

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Tags: HEK293, microcarriers, gene therapy, viral vectors, AAV, upstream