October 21, 2021

Scalable AAV Production Process for Gene Therapy


Viral vectors are often used for gene transfer of specific tissue- or cell-type modifications. Several viruses have been investigated for use in cell and gene therapy; adeno-associated virus (AAV) has emerged as the main vector for gene therapies. Here, we describe how we developed an efficient and scalable cell culture process for AAV production by evaluating and optimizing each process step.

Tags: AAV, viral vectors, cell culture, gene therapy