April 12, 2018

Single-Use Chromatography: Adapting to Manufacturing Scale

AKTA Ready XLSingle-use technologies offer the flexibility needed to meet the demands of multiproduct facilities. The capital investment is lower, and substantial time savings can be made when eliminating cleaning and cleaning validation procedures. While widely adopted in upstream production processes, what is required to move single-use technologies into downstream manufacturing scale? 

This article discusses strategies for meeting the ever-increasing upstream titers and volumes to prevent downstream purification from becoming a bottleneck.

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Tags: ReadyToProcess, prepacked columns, single use, single-use chromatography