December 17, 2015

Benchmarking, scalability, and protein production in CHO cell culture

The most widely used cell lines in the bioprocess industry originate from CHO cells. With the large number  of CHO clones in use, it is important to have a cell culture medium that supports high viable cell counts and  productivity with multiple cell clones. A precise balance of nutrients is crucial for the optimal performance of  these cell clones. ActiPro cell culture medium and feed supplements has a tailored formulation that supports  viable cell counts of more than 25 million cells per mL and protein production greater than 5 grams per liter. High  viable cell density and productivity across multiple CHO cell clones, from shake flasks to 50 L bioreactor cultures, demonstrate the versatility and scalability of the ActiPro medium and Cell Boost supplements.

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