October 19, 2017
Repurposing Fed-Batch Media and Feeds for Highly Productive CHO Cell Perfusion Processes
The authors developed a method for identifying first-generation perfusion culture media based on existing fed-batch media and feeds. Here, they show that they can obtain culture media that successfully support perfusion cultures in bioreactors at cell-specific perfusion rates (CSPR) below 25 pL/cell/day. High productivities and favorable product quality were also achieved.