February 18, 2016

The use of dynamic control in periodic counter-current chromatography


The ÄKTA pcc 75 chromatography system can be used for purification of target proteins in continous downstream processes using periodic counter-current chromatograpy (PCC). This application note shows how the dynamic control functionality of ÄKTA pcc 75 can be used to adjust for variations in binding capacity of the chromatography medium for changes in feed composition, when, for example, perfusion cell culture is being employed.


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