ArticlesDownstream February 9, 2024 Get Started: Purification of mAb Variants – eLearning The success of monoclonal antibodies (mAbs) as therapeutics and the multi-domain structure of... admin-element
Articles January 26, 2024 Chromatography innovations for the diversified antibody pipeline Introducing MabSelect™ VH3 affinity resin for antibody variants. At Cytiva, we connect with... admin-element
ArticlesDownstream April 21, 2023 Optimization of a two-step purification method for bispecific antibodies Bispecific antibodies (bsAbs) have gained increasing interest over recent years because they can... admin-element
ArticlesRegulatory May 20, 2021 Evaluation of Fibro PrismA for Scalable Single-Use mAb Purification In clinical monoclonal antibody (mAb) manufacturing, capture on protein A chromatography resin gives... admin-element
ArticlesBioPharmaDownstream January 17, 2019 A Look at the Affinity Chromatography Landscape Affinity chromatography offers the high selectivity required for biopharmaceutical manufacturing and analysis. Specific binding... admin-element
Articles May 24, 2018 Chromatography Scale-Up: Don’t Get Tied Down by Bed Height When scaling, you can make better use of existing chromatography columns while avoiding overcapacity. admin-element
ArticlesMultimedia May 24, 2018 Cleaning Protein A Resins with 1 M NaOH With increasing mAb titers, the impurity level of the cell culture feed increases. If not… admin-element
ArticlesBioPharmaDownstreamUpstream August 11, 2017 Process Chromatography: Continuous Optimization Cell-culture and fermentation are high-yielding processes that effectively produce... admin-element
ArticlesDownstreamRegulatoryUpstream November 10, 2016 Improving Process-Scale Chromatography Chromatography is a crucial step in the purification of biopharmaceuticals and accounts for a... admin-element
ArticlesDownstream April 8, 2015 Re-use of Protein A Resin: Fouling and Economics In the past two decades, Protein A affinity chromatography has remained the de facto capture… admin-element