Search results for " production" in Posters
Poster
Process economy and production capacity using single-use versus stainless steel fermentation equipment
In comparison with a stainless steel strategy, this study shows that the annual production capacity can be increased up to 100% with a single-use strategy due to a faster batch changeover procedure. T…
Poster
Adenovirus production in a single-use stirring tank bioreactor system
Scalable and cost-efficient production technologies are needed to enable manufacturing of safe and efficacious clinical-grade virus. Anchorage-dependent cells cultured in roller bottles or cell factor…
Poster
A Next Generation Protein A Chromatography Resin for Improved Productivity and Bioburden Control
• The increased upstream titers in mAb production seen in recent years may make the Protein A capture step a bottleneck.
• Protein A columns columns are also more prone to bioburden contamination…
Poster
Development of a chemically defined medium for virus vaccine production in a duck suspension cell line
The primary goal of this project was to develop a chemically defined medium that could be used in a monophasic process while supporting the growth and production of a broad spectrum of different virus…
Poster
Validation of the Production of Influenza Virus
As shear stress is a critical parameter in virus production from anchorage-dependent cells, the possibility to increase working volume to 4 L, without increasing shear forces, was investigated. The re…
Poster
Integration of continuous upstream and downstream operations in mAb production
For a competitive production process, continuous or semi-continuous upstream and downstream processing can be employed. Compared with a process performed in batch runs, continuous processing allows fo…
Poster
Benchmarking, scalability, and protein production in CHO cell culture
ActiPro cell culture medium and feed supplements has a tailored formulation that supports viable cell counts of more than 25 million cells per mL and protein production greater than 5 grams per liter…
Poster
A Scalable Adenovirus Production Process, from Cell Culture to Purified Bulk
In this study, we have combined technical evaluation of process steps and process economy calculations, from AdV production in cell culture to purified bulk product in up to 10 L scale. Human AdV5, ex…
Poster
Repurposing Fed-Batch Media and Feeds for Highly Productive CHO Cell Perfusion Processes
The authors developed a method for identifying first-generation perfusion culture media based on existing fed-batch media and feeds. Here, they show that they can obtain culture media that successfull…
Poster
Strategies for optimized cell culture media: Effectively using design space to influence product quality
Effective biopharmaceutical production is achieved in part through target-specific, quality-optimized cell culture media. Balancing the many individual media components required to achieve high tite…