Search results for " packing"
Article
Efficient Sodium Hydroxide Sanitization with a Novel Procedure of AxiChrom™ Columns Packed with Chromatography Resin
The final version of our method with resin and chemically dependent hold times is highly efficient as an integral part of the packing procedure.
Article
Sanitization of AxiChrom™ Columns Packed with Chromatography Resin
This study evaluates sanitization methods based on 1 M sodium hydroxide (NaOH) as sanitization agent using methodology previously developed for peracetic acid (PAA).
Access study data here…
Article
Process Chromatography Selection for Downstream Processing Applications
… addressed?
Björkman (Cytiva): Some common chromatography column issues include:
• Column packing. Chromatography requires that one packs a stable bed with good flow properties. Earlier colum…
Article
Optimizing Resin Performance with Disposable Chromatography Solutions
Customers have expressed that they feel they have less control over this step if an external supplier performs the packing, rather than it being done in-house. However, once customers start using prep…
Article
SEC in the Modern Downstream Purification Process
…tion and the stationary phase, separations performed using SEC are sensitive to variations in column packing. A properly packed column is vitally important when using SEC, as the number of theoretica…
Article
Single-Use for Downstream Chromatography: Benefit or Hindrance?
Among the common problems that single-use technology can help address is column packing. Column packing requires a stable bed with good flow properties, and, today, automatic packing solutions make pa…
Article
Understanding Validation and Technical Transfer, Part I
FDA, Drugs; Current Good Manufacturing Practice in Manufacture, Processing, Packing, or Holding. In 21 CFR 133, 28 Federal Register 6385, 1963.
2. B. R. Matthews, PDA J. Pharm. Sci. Technol. 56 …
Article
Instructional Videos for Bioprocess Equipment
Modules also cover column packing and maintenance for pilot and process-scale columns.
Each mediabook contains detailed videos for the equipment and the software interface.
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Article
Using Digital Twins to Model Process Chromatography
Data on column packing quality [are] often available as part of column qualification, and conductivity transition data may provide an insight in fluid mechanics often overlooked. Data on buffer compos…
Article
Strategizing for Rapid Changeovers in Biologics Manufacturing
“Operational excellence/lean methodologies can be quite powerful for optimizing changeover processes, as can the use of redundant equipment or dedicating packing rooms for chromatography columns. In t…