Search results for " multivariate data analysis"

Article Use of Multivariate Data Analysis in Bioprocessing
Figure 1: Flowchart illustrating the general workflow of multivariate data analysis (MVDA) of bioprocessing data. MVDA applications in cell-culture operations Cell-culture operations are by far…

Article Remote Monitoring and Big Data Advance Upstream Automation
The key component to all of this is software capable of integrating the variety of lab equipment and resulting data allowing for multivariate data analysis and process control,” he says. Notable r…

Article Assessing Manufacturing Process Robustness
A structured assessment process can determine compliance to lifecycle process-validation requirements for biopharmaceuticals. By: Ajay Pazhayattil, Sanjay Sharma, Amol Galande, Marzen…

Article Setting Up Bioprocessing Systems for Digital Transformation
Digitalization of bioprocessing operations, equipment, and facilities can improve workflow and output, but maintaining data integrity is a concern. By Feliza Mirasol The advancement of digit…

Article A Platform Approach for the Identity Testing of Multi-Component Cell-Culture Media
Therefore, NIR does not provide specific identity of the studied material and requires a use of spectral libraries or multivariate data analysis (MVDA) for spectra evaluation. NIR spectroscopy is a ve…

Article Digitalization: The Route to Biopharma 4.0
The industry realizes that there is a limit on the number of experiments that is feasible, and, hence, extensive use of methodologies such as design of experiments and multivariate data analysis is be…

Article Maximizing the Effectiveness of Upstream Bioprocessing Through the Combination of Lab Informatics and Instrumentation
High-throughput techniques such as micro-bioreactor systems are another enabling technology, which, in combination with design of experiments (DoE) and multivariate data analysis (MVDA), support a qua…

Article Determining Criticality–Process Parameters and Quality Attributes Part III: Process Control Strategies—Criticality throughout the Lifecycle
The author applies the continuum of criticality to develop the process control strategy and move through Stages 2 and 3 of the new process validation lifecycle. With the most recent FDA …

Article Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
Second, better systems for collecting, storing, and analyzing process data have facilitated the application of multivariate data analysis (MVDA) to historical bioprocess data. These developments have …

Article Moving PAT from Concept to Reality
“Some concepts of modern automation technologies and sensor technologies are not yet covered by regulatory guidelines, particularly those used for multivariate data analysis, which takes all available…

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