Search results for " HiScale 10/40"

Article New HiScale™ 10/40 for Scale-Down Studies
GE Healthcare Life Sciences is pleased to announced the new HiScale™ 10/40. HiScale 10/40 column is especially suitable for scale-down studies used in, for example, viral clearance evaluation in dow…

Article Process scale-up from HiScreen™ to HiScale™ columns
In this study two capture purification steps were scaled up from HiScreen to HiScale columns in order to evaluate process reproducibility and robustness. The two media used, MabSelect SuRe™ and Capto…

Multimedia How to pack a HiScale™ column
This video will guide you through the steps of how to pack a HiScale™ column from GE Healthcare.

Article New Guide for Packing HiScale, XK, and Tricorn Columns
This guide summarizes parameters for packing small-scale HiScale™, XK, and Tricorn™ columns with Capto and MabSelect resins from GE Healthcare Life Sciences. Download the Packing Guide

Article Capture of human single-chain Fv (scFv) fusion protein on Capto L affinity medium
We describe the capture of a single-chain Fv fusion proteinfrom a challenging feedstock (animal plasma) on the affinitychromatography medium (resin) Capto™ L. Initial work on smallprepacked HiScreen™ …

Article High-throughput process development and scale-up of an intermediate purification step for recombinant insulin
This Application note describes high-throughput process development with PreDictor™ plates and Assist software to develop the intermediate purification step of insulin derived from E. coli. This rev…

Tip Columns for process development and scale-up
Modern media like the Capto™ range and the MabSelect™ family offer improved performance features such as high binding capacities, high flow rates, novel selectivities, and optimized efficiency. Howe…

Article Case Study: Virus Reduction of an Affinity Capture Step
Evaluating how much a process step contributes to viral clearance is an essential part of process validation. For this reason, there is an industry need to perform effective viral clearance studies. I…

Article Multidimensional Scale-Up of a Monoclonal Antibody Capture Step, Using ÄKTA™ pilot 600
Fast and efficient process development and scale-up contributes to a shortened time to market. In this work, a multidimensional scale-up (change of both column diameter and bed height) of a mAb capt…

Article Downstream scale-up purification of influenza virus using ReadyToProcess equipment
This application note describes a case study where live influenza virus was purified using single-use ReadyToProcess technology. The ReadyToProcess platform is a flexible manufacturing solution, whi…

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