Search results for "adeno-associated viruses; AAV" in Articles / App Notes

Article The GMP of AAV: Purification for Clinical Production
Watch this presentation to learn about the key considerations when developing a purification process for adeno-associated viruses (AAV).  >>> Learn more

Article Scalable AAV Production Process for Gene Therapy
Read more >> Viral vectors are often used for gene transfer of specific tissue- or cell-type modifications. Several viruses have been investigated for use in cell and gene therapy; adeno-associ…

Article Gene Therapies Push Viral Vector Production
Gene Therapies Push Viral Vector Production Viral vectors show promise as a delivery mechanism for gene therapy, but which virus types are commercially viable? By Feliza Miraso…

Article Ensuring Viral Safety of Viral Vaccines and Vectors
Ensuring Viral Safety of Viral Vaccines and Vectors Viral vaccines and viral vectors used in biotherapeutic applications carry the risk of microbial contamination, which must be addressed. …

Article A Look at the Affinity Chromatography Landscape
A Look at the Affinity Chromatography Landscape New ligands are being developed to meet the separation and purification needs of next-gen biologics. By Cynthia A. Challener …

Article Scaling Up Novel Therapies
Scaling Up Novel Therapies Platform processes have improved monoclonal antibody scale-up. Can they do the same for personalized therapies? By Agnes S…

Article Production of Recombinant Adeno-associated Virus Vectors Using Microcarrier Culture of HEK293T Cells
As of March 2020, more than 4310 gene therapy clinical trials have been performed worldwide, with only 518 of them in Phase III and Phase IV. As the gene therapy projects enter clinical Phase III or g…

Article Technology Innovations Improve Process Chromatography Performance
As technology matures, inefficiencies and process limitations in downstream process chromatography are improved. By Feliza Mirasol Selecting an appropriate separation technology fo…

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