Search results for " mechanistic modeling" in Articles / App Notes
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Mechanistic Modeling of Preparative Ion-Exchange Chromatography
For complex unit operations such as process chromatography, mechanistic modeling can assist in developing a systematic approach for process development, monitoring, and control. Models can also be jud…
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Mechanistic Modeling: Does it Have a Future in Process Development?
Most often, the DoE approach is preferred based on a cost-benefit evaluation where the time consumption, complexity, and lack of know-how on how to deploy are found too extensive when using mechanisti…
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Mechanistic Modeling: Current Advantages and Future Opportunities in Biopharmaceutical Process Development
This week, Bioprocess Development Forum spoke with Tobias Hahn, PhD, co-founder and CEO of GoSilico, about the opportunities of mechanistic modeling in bioprocess development, now and in the future.
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Insider Recommendations for Getting Started with Mechanistic Modeling of Chromatography
Topics covered include:
0:45 - What is mechanistic modeling of chromatography?
3:47 - Obstacles to implementing mechanistic modelling.
5:10 - Top tips for implementing mechanistic modeling…
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Why use mechanistic modeling in downstream process development?
With mechanistic models, process developers can get a better understanding of both the entire process and the parameters that can …
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FAQ: Scale-up and scale-down with mechanistic modeling
…fects, choose the correct scale for model calibration, and understand how scale-up integrates into a mechanistic modeling workflow.
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Utilization of Mechanistic Modeling to Improve Process Development
Utilization of mechanistic modeling of unit operations, based on scientific and physical understanding of the process, is one of these approaches. Improved computational resources in the past decade h…
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Mechanistic modeling quiz
Mechanistic models make it possible to create computer simulations of chromatograms. The simulations are based on physiochemical phenomena known to occur in chromatography. The benefit of a me…
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Advanced therapeutics process development using mechanistic modeling
what the challenges are in process development when working with both diverse molecules and mechanistic modeling.
MORE Q&As WITH INDUSTRY LEADERS >>
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How to put mechanistic modeling into practice
Make it happen! Learn about insider recommendations to get started with in silico process development.
Check out our resources on good modeling practice, case studies, and other publication…