Search results for " miniaturization"

Article Modeling and Miniaturization: Key Topics at Successful HTPD Conference
Modeling and miniaturization were two key take-home messages from the 4th High Throughput Process Development (HTPD) conference organized in October 2017 in Toledo, Spain. The conference brought tog…

Article Miniaturization to Become Even More Successful
Industrial bioprocess development has changed significantly in the last decade, driven primarily by two major factors: ever-rising R&D costs of developing therapeutic candidates with simultaneous de…

Article Tools for Continuous Bioprocessing Development
In response to the increasing need for parallelization and miniaturization of controlled and monitored bioreactors, commercial and academic research groups have developed microbioreactors with working…

Article Optimizing Late-Stage and Commercial Cell-Culture Processes
Other innovations, such as culture miniaturization with representative systems, permits testing of many culture conditions in a short period of time. In addition, development of intensified processes …

Article Combining Microbioreactors and Advanced Statistical Techniques to Optimize a Platform Process for a New Host-Cell Line
Use of a subspace model is a viable method to characterize process space variables and optimize process performance. By Colin Jaques, Daniela Lega Over the past decade, two improved capabili…

Article Modular Manufacturing Platforms for Biologics
May 01, 2015 By Randi Hernandez BioPharm International Volume 28, Issue 5 It should come as no surprise that the good design principles governing the execution of pharmaceutical manu…

Article 2019 HTPD Conference Is Announced. What Happened Last Time?
The 5th international conference devoted to high-throughput process development (HTPD) and smart PD, will take place November 4-7, 2019 in Porto, Portugal.   HTPD 2019 (sponsored by GE Healthca…

Article Advances in Engineering of Protein-Based APIs
Similarly, miniaturization and high-throughput versions of protein assays will reduce analysis times and enable exploration of wider design spaces. Stevens points to nanofluidic characterization assay…

Article Platform Approach Speeds Process Development
A modular cell-culture platform demonstrates accelerated process development. By Harald Bradl, Jan Bechmann, Benedikt Greulich, Markus Michael Mueller, Patrick Schulz, Thomas Wucherpfennig C…

Article Implications of Cell Culture Conditions on Protein Glycosylation
The authors present a review of the techniques commonly used for glycosylation analysis. By Michiel E. Ultee, PhD, Dr. Richard Easton This article reviews the implications of cell-culture co…

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