Search results for " mixing"

Article The use of Xcellerex™ mixing system as slurry tank when packing chromatography columns
 The capability of the mixing system to keep the chromatography medium (resin) in suspension and the possibility to integrate the system in column packing were studied. The results show that XDM Quad …

Article Mixing dynamics in a large volume single use mixer
Large-volume mixers are mainly required in clinical three-scale and production-scale facilities where  mixing efficiency is one of the key drivers of throughput efficiency. Upstream applications such …

Poster Heating-cooling and liquid-liquid mixing characterization at a range of volumes
Heating/cooling and mixing properties are the two key parameters important for mixing applications and are needed when comparing the performance between stainless-steel and single-use mixers. In this …

Article Using Xcellerex™ mixing system as a slurry tank when packing chromatography columns
The capability of the mixing system to keep the chromatography medium (resin) in suspension and the possibility to integrate the system in column packing were studied. Further, an evaluation of the ef…

Article Fundamentals of Mixed Mode (Multimodal) Chromatography
Visit the site >> Check out Cytiva’s new resource hub for multimodal chromatography!

Article Tools for Continuous Bioprocessing Development
A paper from ETH Zurich (funded by Novartis) demonstrated that geometric similarity fundamentally does not allow for scale invariance (from 3 L to 15,000 L) of kLa, shear stress, and mixing time simul…

Article Single-use Bioreactors Have Reached the Big Time
“When considering the workflow and objectives of running bioreactors, recent developments have focused on reducing complexity, improving mixing to achieve higher volumetric mass transfer coefficients …

Article Modeling Bioreactor Performance
In general, process-specific data must also be generated to perform these modeling studies because oxygen transfer and mixing times differ depending on the medium used and the bioreactor fill volume a…

Article Process Chromatography Selection for Downstream Processing Applications
Also, the ability to use concentrated buffer components and mixing them in-line under controlled conditions (in-line conditioning) has simplified the chromatographic operation. Other simplifications a…

Article Cell-Culture Advances Test Bioreactor Performance Models
“Viscosity and solution property changes can fundamentally change mass-transfer mechanisms by impacting bubble size, bubble coalescence, mixing times, shear rates, and other parameters,” he explains. …

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