Search results for " viral vector"

Article Gene Therapies Push Viral Vector Production
By Feliza Mirasol  Several virus types have been studied for use as viral vectors in gene therapy, including adenovirus, lentivirus, retrovirus, and adeno-associated virus (AAV). Of these, AA…

Article Ensuring Viral Safety of Viral Vaccines and Vectors
Moreover, such events could affect the broader perception of vaccine and viral vector safety. This article outlines the risks and challenges associated with managing viral safety in virus vacci…

Article Flexible Facilities for Viral Vector Manufacturing
“In the viral vector space, there is diversity around different vector types (e.g., lentivirus [LV], adenovirus [AV], and adeno-associated virus [AAV]). It’s critical to have a facility design that is…

Article Scalable Viral Vector Manufacturing
What are the main reasons for this rapid increase in viral vector manufacturing? Viral vector platforms emerging at the crossroads of cell, gene therapy, and vaccines are becoming a promising ar…

Article Achieve Scalable Viral Vector Production
In our tutorial series on viral vector production, GE scientists share their insights on virus production and how to tackle viral vector manufacturing challenges. In this episode, a scalable productio…

Article Manufacturing of Viral Vectors
In gene therapy, viral vectors can be used for the delivery of functional genes to replace defective genes to cure genetic disorders. As a vaccine platform, viral vectors can be used for the expressio…

Article Tips for Viral Vector Production
In this blog article, insights are shared around the challenges in viral vector manufacturing and how to achieve a scalable and cost-efficient process suitable for GMP manufacturing environments. …

Article Manufacturing of Vaccines and Viral Vectors
In this article, general guidelines for scaling up a viral vector and virus manufacturing processes are discussed. The case study is based on adenovirus and the results show a cost-efficient productio…

Article Lentiviral Vector Upstream Process in Single-use Bioreactors
Lentiviruses exhibit many desirable properties as gene transfer vehicles, such as high transduction efficiencies, ability to infect both dividing and nondividing cells, and stable integration into t…

Poster Process economy modeling for viral vector production
Viral vectors, such as adenovirus, adeno-associated virus, and herpes simplex virus, can be used in cancer therapeutics and in vaccines for chronic diseases and are thus expected to become high-valu…

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