Search results for " MabSelect" in Articles / App Notes
Article
Re-use of Protein A Resin: Fouling and Economics
Some of the major Protein A resins that are commercially available include MabSelect (Cytiva), MabSelect Xtra (Cytiva), MabSelect SuRe (Cytiva), MabSelectSuRe LX (Cytiva), ProSep Ultra Plus (EMD Milli…
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Process Economy Simulations on a Protein A Capture Step
This application note gives calculation examples that highlight scenarios where the enhanced capacity and alkaline‐stability of MabSelect PrismA can provide process economic benefits to large‐scal…
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Capacity and Performance of a Next Generation Protein A Chromatography Resin
The resin exhibits improved capacity over its predecessor MabSelect SuRe™ products, while maintaining purification performance. This application note demonstrates the binding capacity and purification…
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Chromatography innovations for the diversified antibody pipeline
Our MabSelect™ VH3 affinity resin interacts with the variable heavy chain of the VH3 sequence family of human antibody, delivering high binding capacity and efficient separation of product-related imp…
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As the therapeutic pipeline diversifies, chromatography toolboxes are expanding.
Cytiva expands the antibody capture resin toolbox and has recently announced MabSelect™ VH3 affinity resin. MabSelect VH3 uses an engineered protein A resin that interacts only with the variable heavy…
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Protein L affinity resin is ready to move to manufacturing
The MabSelect™ VL protein L resin now offers improved alkaline stability compared to Capto™ L resin and a two-fold or more increase in dynamic binding capacity (DBC) in certain applications. After com…
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Comparing Protein A Resins for Monoclonal Antibody Purification
A team from Chugai Pharmaceutical (Japan) investigated the mAb purification performance of a new alkali-tolerant, prototype Protein A resin (Resin 3, MabSelect SuRe LX prototype, Cytiva), which has th…
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Top Tips for Successful Development of Antibody Chromatography Processes
But working with protein L, that only binds kappa subclass one, three and four, for instance, MabSelect™ VL, you could get a really high purity sample during the capture step. Since the lambda heterod…
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Detailed agenda for Chromatography + filtration virtual summit
We will also discuss recent innovations, such as Cytiva™ Protein Select™ technology, MabSelect™ VH3 resin, and MabSelect VL resin.
Registration is free of charge - see you there!
Register for …
Article
Chromatography for the Diversified Antibody Pipeline
It may place more work on the main polishing steps, however, MabSelect may interact with the classes of DH3 in the antibodies—which enables separations targeting the constant DC region. We can see the…