Search results for " viral vector production"

Article Gene Therapies Push Viral Vector Production
Another manufacturing challenge in viral vector production, Murphy points out, is the development and qualification of robust analytical methods to measure product quality. “At the present time…

Article Antibody Production in Microbial Hosts
The authors review the status of expression of antibodies in microbial hosts and present the recent advances in the production of aglycosylated antibodies in bacteria. By Anurag S. Rathore, Jyot…

Article Achieve Scalable Viral Vector Production
In our tutorial series on viral vector production, GE scientists share their insights on virus production and how to tackle viral vector manufacturing challenges. In this episode, a scalable productio…

Article Tips for Viral Vector Production
The viral vector market is highly active, and the interest in production technologies is driven by recent approvals in cell and gene therapy. In this blog article, insights are shared around the cha…

Poster Process economy modeling for viral vector production
Viral vectors, such as adenovirus, adeno-associated virus, and herpes simplex virus, can be used in cancer therapeutics and in vaccines for chronic diseases and are thus expected to become high-valu…

Article Achieving Efficient Adenovirus Upstream Production
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and vaccines against infectious diseases. Adenovirus has also been explored as a viral vector f…

Article Case Study: Process for Production of Oncolytic Adenovirus
The promising results from clinical studies on the use of viral vectors to address important medical needs have spurred interest in developing scalable and cost-efficient manufacturing processes. Here…

Article Evaluation of HEK293 Cell Growth and Adenovirus Productivity in HyClone™ CDM4HEK293 Medium
Human embryonic kidney 293 (HEK293) cells are widely used in production of recombinant viruses and proteins because of their stable growth, high transfection level, and ability to produce high viral t…

Poster A Scalable Adenovirus Production Process, from Cell Culture to Purified Bulk
Adenovirus (AdV) vectors are commonly used in cancer gene therapy trials and evaluated for use in vaccines for various diseases. In this study, we have combined technical evaluation of process steps a…

Poster A Scalable Adenovirus Production Process
The promising results from clinical studies on the use of viral vectors to address important medical needs have spurred interest in developing scalable and cost-efficient manufacturing processes. To…

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