Search results for " cell culture"

Article Cell-free Expression Systems Pose Cell Culture Alternative
Feliza Mirasol Among the challenges in upstream bioprocessing is the cellular waste generated as a by-product of cell culture. One approach that potentially offers the benefit of a “cleaner”…

Article Implications of Cell Culture Conditions on Protein Glycosylation
In mammalian cell culture processes, the use of different species can potentially produce significant differences in the types of glycosylation that can occur. These differences in glycosylation can h…

Article What’s in your media? How costly is variability of cell culture media to your manufacturing process?
Today we are going to discuss what is your media and how costly variability of the cell culture media is to the manufacturing process. I am Megan Manzano, senior editor for BioPharm Interantional. Joi…

Poster Benchmarking, scalability, and protein production in CHO cell culture
With the large number  of CHO clones in use, it is important to have a cell culture medium that supports high viable cell counts and  productivity with multiple cell clones. A precise balance of nutri…

Article Optimization of Fed‑Batch Culture Conditions for a mAb‑Producing CHO Cell Line
This application note describes a broadly applicable and efficient workflow toward finding the optimal feed combination for the best-performing fed-batch processes.  An IgG1-producing CHO cell

Article Fed-batch supplements to boost cell culture performance
This application note demonstrates the enhanced performance of commonly used cell lines for MAb production when supplemented with HyClone™ cell culture supplements. Cultures of Chinese hamster ovary (…

Multimedia Cell Culture Media Considerations and Optimization for Improved Titers and Protein Quality
Peggy Lio, Senior Director of Global Cell Culture Services at Cytiva, explores the evolution of bioprocessing over the last 30 years, parameters to consider when developing cell culture media, and wha…

Article Cell Culture Media Considerations and Optimization for Improved Titers and Protein Quality
Related Content Q&As with Industry Leaders      Learn more about our Cell Culture Services View our Cell Culture Media and Feeds Read our case study on Improving Cell Cultu…

Poster Scale-up of CHO fed-batch cultures in HyClone™ ActiPro™ medium supplemented with Cell Boost™ 7a and 7b
Comparing cell growth and recombinant protein production of multiple Chinese hamster ovary (CHO) cell clones when cultured in HyClone ActiPro basal medium and Cell Boost 7a and 7b feeding supplement…

Poster Strategies for optimized cell culture media: Effectively using design space to influence product quality
Here we highlight a statistical design strategy to optimize cell culture media to influence the charge variant profile of a mAb produced in CHO DG44 cells.    Media optimization requires incorp…

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