Search results for "bioreactor"

Article Single-use Bioreactors Have Reached the Big Time
Challener Single-use bioreactors available from various vendors today are robust and provide the high-performance necessary for commercial manufacturing of biopharmaceuticals. Significant advances…

Article Cell-Culture Advances Test Bioreactor Performance Models
Challener  Modeling and simulation are recognized to provide assistance in predicting bioreactor performance, both for initial laboratory runs and when scaling to the pilot plant and commercial ma…

Article Trends in Single-use Bioreactors
By: Randi Hernandez While the overall trend toward single-use bioreactors is generally positive, users continue to have some concerns, limiting the widespread implementation of these technologies…

Article Achieving Process Balance with Perfusion Bioreactors
With recent availability of perfusion bioreactors and novel cell retention technologies, there is a renewed interest in perfusion cell culture,” notes Peter Levison, executive director of business dev…

Article Modeling Bioreactor Performance
Challener Bioreactor design, including the geometry of the tank and impeller and the locations of inlets, has a direct impact on the performance of cell-culture and fermentation processes. Modelin…

Article Highly efficient inoculum propagation in perfusion culture using WAVE Bioreactor™ systems
All cultures were grown in disposable Cellbag™ bioreactors using the WAVE Bioreactor system. Cell concentrations of 4.8 × 107 cells/mL were achieved in perfusion culture, whereas the final cell concen…

Article Large-scale cell culture using Cellbag™ bioreactors with embedded optical sensors
 For related literature, see:  WAVE Bioreactor 200 system, Data file 29-0237-13; Disposable Cellbag bioreactors for WAVE Bioreactor systems, Data file 28-9511-36 Introduction Dis…

Article New ReadyToProcess WAVE 25 Bioreactor Provides Advanced Control in Research, Process Development, and Manufacturing Operations
When it was first introduced in 1996, the WAVE Bioreactor, with its unique rocking motion, was an effective, breakthrough single-use technology for biopharmaceutical manufacturing. In 2013, GE Healthc…

Article Vaccine process development using Cytodex™ microcarriers in WAVE™ Bioreactor systems
In this study, Cytodex microcarriers were used in Cellbag™ bioreactors to expand Madine-Darby Canine Kidney (MDCK) and Vero cells. Different mixing conditions were tested for both cell lines in order …

Article Propagation of influenza virus in Vero cells using Cytodex microcarriers in WAVE Bioreactor systems
As part of optimizing the conditions for cell growth in WAVE Bioreactor system, the effects of a number of supplements and different rocking conditions were evaluated. Next, in order to find the optim…

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