Search results for "bioreactor"

Article Single-use Bioreactors Have Reached the Big Time
Challener Single-use bioreactors available from various vendors today are robust and provide the high-performance necessary for commercial manufacturing of biopharmaceuticals. Significant advances…

Article Cell-Culture Advances Test Bioreactor Performance Models
Challener  Modeling and simulation are recognized to provide assistance in predicting bioreactor performance, both for initial laboratory runs and when scaling to the pilot plant and commercial ma…

Article Trends in Single-use Bioreactors
By: Randi Hernandez While the overall trend toward single-use bioreactors is generally positive, users continue to have some concerns, limiting the widespread implementation of these technologie…

Article Achieving Process Balance with Perfusion Bioreactors
With recent availability of perfusion bioreactors and novel cell retention technologies, there is a renewed interest in perfusion cell culture,” notes Peter Levison, executive director of business dev…

Article Modeling Bioreactor Performance
Challener Bioreactor design, including the geometry of the tank and impeller and the locations of inlets, has a direct impact on the performance of cell-culture and fermentation processes. Modelin…

Poster Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
Here, we describe different approaches for the cultivation of Vero cells using Cytodex and Cytodex Gamma microcarriers in serum-free cultivation medium using spinners, WAVE Bioreactor™ 20/50, ReadyToP…

Article Validation of the production of influenza virus in ReadyToProcess WAVE™ 25 bioreactor system
This application note describes the validation of the single-use ReadyToProcess WAVE 25 rocking bioreactor system in production of influenza virus from Vero cells in microcarrier-based cultures. A 2…

Article ReadyToProcess WAVE 25 Bioreactor System
The system is based on a well-known rocking technology that provides mixing and aeration to the culture, which is maintained in an inflated, disposable Cellbag bioreactor cultivation chamber. With…

Poster Adenovirus production in a single-use stirring tank bioreactor system
In this work we demonstrate an efficient process for adenovirus production in a single-use stirred-tank bioreactor, using HEK293 cells adapted for suspension culture. Human adenovirus 5 expressing gre…

Article Scaling a mAb Production Process to Xcellerex Bioreactors
This article discusses moving a monoclonal antibody (mAb) production process from a microscale bioreactor to the Xcellerex XDR single-use platform. Learn more >>

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