Search results for "Column packing; chromatography; pro…"

Article Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
Optimization of each phase in a chromatographic cycle has a positive impact on productivity. By Anna Grönberg An important area of focus for the biopharma industry is the elucidation and dev…

Article Ready-to-use fluid management for inline conditioning (IC) large-scale chromatography systems
There is an increasing interest in IC systems because they; (i) are relatively customizable; (ii) reduce the need for large storage tanks, and (iii) are economical. These features combine well with …

Article Improvements in Protein A Chromatography
Process Development Forum speaks about Protein A chromatography with Glen Bolton, Scientific Director at Amgen. Bolton recently published a paper “Role of more than 40 years of improvement in Protei…

Tip Prepacked chromatography columns for ÄKTA™ systems
Today’s challenges within biopharmaceutical process development include swift and secure handover of robust processes where time is often a limiting factor. With prepacked columns, time can be saved…

Article Vocabulary for Chromatography Column Packing
Click here to learn more >> Packing a chromatography column is an art in itself and requires a certain level of expertise. Here, we provide definitions for common terminology used in column pa…

Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
Bioterminology: A Guide to the Biopharmaceutical Lexicon This lexicon was generated by the editors of BioPharm International magazine. Please feel free to email your suggestions for terms that s…

Article Economic drivers and trade-offs in antibody purification processes
The future of therapeutic MAbs lies in the development of economically feasible downstream processes.  By Suzanne S. Farid, PhD  ABSTRACT Increasing titers in mammalian cell culture has rec…

Article Challenging the cleanroom paradigm for biopharmaceutical manufacturing of bulk drug substances
The authors re-examine environmental controls in the context of technical advances in manufacturing.  By Simon Chalk, Scott Probst, Paul Gil, Tim Palberg, Matt Kennedy, Joe Rogalewicz, Jeff Johns…

Article Purification Strategies to Process 5 g/L Titers of Monoclonal Antibodies
Altering the order of operations, using new resins, and increasing dynamic binding capacity can obviate the need for major facility changes. By Melody Trexler-Schmidt, Stefanie Sze-Khoo, Amber R…

Article Scaling Up Novel Therapies
Scaling Up Novel Therapies Platform processes have improved monoclonal antibody scale-up. Can they do the same for personalized therapies? By Agnes Shan…

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