Search results for " hyclone"

Poster Scale-up of CHO fed-batch cultures in HyClone™ ActiPro™ medium supplemented with Cell Boost™ 7a and 7b
Comparing cell growth and recombinant protein production of multiple Chinese hamster ovary (CHO) cell clones when cultured in HyClone ActiPro basal medium and Cell Boost 7a and 7b feeding supplement…

Article Evaluation of HEK293 Cell Growth and Adenovirus Productivity in HyClone™ CDM4HEK293 Medium
Human embryonic kidney 293 (HEK293) cells are widely used in production of recombinant viruses and proteins because of their stable growth, high transfection level, and ability to produce high viral t…

Article A Global Footprint
HyClone™ cell culture media, sera, and process liquids, now part of GE Healthcare.  Commenting on the acquisition, Kieran Murphy, President and CEO of GE Healthcare’s Life Sciences business say…

Article Optimization of Fed‑Batch Culture Conditions for a mAb‑Producing CHO Cell Line
This application note describes a broadly applicable and efficient workflow toward finding the optimal feed combination for the best-performing fed-batch processes.  An IgG1-producing CHO cell l…

Article Fed-batch supplements to boost cell culture performance
This application note demonstrates the enhanced performance of commonly used cell lines for MAb production when supplemented with HyClone™ cell culture supplements. Cultures of Chinese hamster ovary (…

Article Achieving Efficient Adenovirus Upstream Production
Adenovirus is one of the most frequently used viral vectors in the development of therapeutic vaccines and vaccines against infectious diseases. Adenovirus has also been explored as a viral vector f…

Poster Effects of feeding strategy on CHO cell performance in fed-batch cultures
ActiPro cell culture production medium is intended to be used in combination with Cell Boost 7a and 7b supplements to enhance recombinant protein production in fed-batch or perfusion processes. This…

Poster Scale-up and process economy calculations of a dAb purification process using ready-to-use products
Purification of a domain antibody (dAb) in a chromatography capture step was successfully scaled from laboratory to pilot scale using ready-to-use equipment and ready-made buffers. The scaled-up pro…

Article Make buffer preparation more time and cost efficient with inline conditioning
GE's extensive HyClone™ buffer and process liquids portfolio include stock solutions suitable for in-line conditioning. Both standard formulations and customized solutions are available. To learn …

Poster Benchmarking, scalability, and protein production in CHO cell culture
The most widely used cell lines in the bioprocess industry originate from CHO cells. With the large number  of CHO clones in use, it is important to have a cell culture medium that supports high via…

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