Search results for " multidimensional" in Articles / App Notes
Article
Multidimensional Scale-Up of a Monoclonal Antibody Capture Step, Using ÄKTA™ pilot 600
In this work, a multidimensional scale-up (change of both column diameter and bed height) of a mAb capture step, using the ÄKTA pilot 600 chromatography system, is demonstrated. Column volume per…
Article
Web Chat June 19: Challenge Cytiva Scientists with Multistep Purification
Automated multistep (or multidimensional) protein purification is used to free up time, increase throughput, and reduce intermediate sample storage.
Join us for a free, one-hour web chat to dis…
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Application of Quality by Design to Viral Safety
Identification of a multivariate design space in which data support the impact that multidimensional process parameter ranges will have on critical quality parameters enables process consistency. The …
Article
Good Modeling Practice
Multicomponent feed stocks lead to multidimensional parameter estimation problems with many unknown protein parameters. Standard model calibration techniques may result in unreasonable correlations an…
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Setting Up Bioprocessing Systems for Digital Transformation
But how would this work? Hahn answers that question by explaining that AI, multivariate, and mechanistic models serve to better interpret complex, multidimensional data, which therefore enables improv…
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Biosimilar Quality Requirements
Meanwhile, though it is possible to use methods such as multidimensional nuclear magnetic resonance or X-ray crystallography to obtain more detailed analysis of higher-order structures, these methods …
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Methods Accelerate Biosimilar Analysis
It is possible to use multidimensional nuclear magnetic resonance (MD–NMR) or X-ray crystallography to obtain detailed analysis of both secondary, tertiary, and—as applicable—quaternary structures, bu…
Article
Multistep Protein Purification: Gain Time and Consistency
In this webinar, "Gain Time and Add Consistency with Automated Multistep Protein Purification," the presenters discussed the benefits of automation, how to set up an automated purification protocol,…
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Your Source of Information for Automated Multistep Protein Purification
Increasing the level of automation in protein purification can free up time and allow other tasks to be performed while the chromatography system is working. Cytiva has gathered recourses to support a…
Article
Robust Optimization, Simulation, and Effective Design Space
ICH Q8, Pharmaceutical Development (1) defines a design space as: “The multidimensional combination and interaction of input variables (e.g., material attributes) and process parameters that have been…