Search results for " buffer dilution"

Article Will My Buffers Work When Using an Inline Conditioning System?
Buffer preparation can be both time and space consuming and can easily become a challenge in biomanufacturing. In-line preparation of buffers from highly concentrated, single-component stock soluti…

Article Overcoming Buffer Challenges With In-Line Conditioning
Preparation and storage of the large number of buffers required for biopharmaceutical production can be a challenge, particularly in large production scale. In this application note, we show how in-…

Poster Overcoming buffer challenges in plasma production with in-line conditioning
Buffer preparation in the plasma industry is a challenge. One industry trend is in-line dilution to reduce the floor space needed for buffer preparation and storage as well as to enable the use of b…

Article Four Purification Steps with Buffer Dilutions in One Go? No Problem!
Free up time by automating the protein purification and by reducing manual interactions. Learn how Shin Isogai at Biozentrum, Basel, harnesses automation to purify more proteins per week using &Auml…

Article Purification Strategies to Process 5 g/L Titers of Monoclonal Antibodies
Inline buffer dilution and bioprocess bags: An integrated approach. IBC Biopharmaceutical and Development Manufacturing Summit; 2006 December 6–7; Orlando, FL. 8. Norling L, Chen Q, Blank, G. Esta…

Article Process Chromatography Selection for Downstream Processing Applications
Industry experts discuss best practices for selecting a separation technology. By Caroline Hroncich Process chromatography has changed significantly since it was first introduced to the biop…

Article Practical considerations for demonstrating drug substance uniformity
The authors describe considerations and best practices for meeting drug substance uniformity. By Sushil Abraham, Eric Rydholm, and Phil Wagner ABSTRACT Drug-substance uniformity is an impo…

Article Polishing of Monoclonal Antibodies using Capto™ MMC ImpRes in Bind and Elute Mode
A rapid procedure to establish a robust second step in bind/elute (B/E) mode for the purification of a MAb using Capto MMC ImpRes has been developed. This study presents results from optimization …

Article Improving Process-Scale Chromatography
Advances in technology are increasing the productivity and efficiency of commercial-scale chromatography bioprocesses. By Cynthia Challener, PhD Chromatography is a crucial step in the purif…

Article Ready-to-use fluid management for inline conditioning (IC) large-scale chromatography systems
There is an increasing interest in IC systems because they; (i) are relatively customizable; (ii) reduce the need for large storage tanks, and (iii) are economical. These features combine well with …

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