Search results for " bioreactors"

Article Single-use Bioreactors Have Reached the Big Time
Challener Single-use bioreactors available from various vendors today are robust and provide the high-performance necessary for commercial manufacturing of biopharmaceuticals. Significant advances…

Article Trends in Single-use Bioreactors
By: Randi Hernandez While the overall trend toward single-use bioreactors is generally positive, users continue to have some concerns, limiting the widespread implementation of these technologies…

Article Achieving Process Balance with Perfusion Bioreactors
With recent availability of perfusion bioreactors and novel cell retention technologies, there is a renewed interest in perfusion cell culture,” notes Peter Levison, executive director of business dev…

Article Modeling Bioreactor Performance
Typically, modeling programs are used to quantitatively describe and understand the behavior of different types and scales of bioreactors. Most widely used are commercially available computational flu…

Article Highly efficient inoculum propagation in perfusion culture using WAVE Bioreactor™ systems
All cultures were grown in disposable Cellbag™ bioreactors using the WAVE Bioreactor system. Cell concentrations of 4.8 × 107 cells/mL were achieved in perfusion culture, whereas the final cell concen…

Article Large-scale cell culture using Cellbag™ bioreactors with embedded optical sensors
 For related literature, see:  WAVE Bioreactor 200 system, Data file 29-0237-13; Disposable Cellbag bioreactors for WAVE Bioreactor systems, Data file 28-9511-36 Introduction Dis…

Article New ReadyToProcess WAVE 25 Bioreactor Provides Advanced Control in Research, Process Development, and Manufacturing Operations
Next-generation WAVE Bioreactor™ from GE Healthcare Life Sciences provides state-of-the-art intelligent and accurate process control combined with true ease-of-use. When it was first …

Article Vaccine process development using Cytodex™ microcarriers in WAVE™ Bioreactor systems
In this study, Cytodex microcarriers were used in Cellbag™ bioreactors to expand Madine-Darby Canine Kidney (MDCK) and Vero cells. Different mixing conditions were tested for both cell lines in order …

Article Propagation of influenza virus in Vero cells using Cytodex microcarriers in WAVE Bioreactor systems
WAVE Bioreactor 20/50 system using a single-use Cellbag* bioreactor (Fig 1) offers easy set-up with no cleaning required, making it a fast and convenient alternative to stainless steel bioreactors.  …

Poster Validation of Cytodex™ Gamma microcarrier-based virus production in single-use bioreactor systems
A majority of cell lines commonly used for viral vaccine production are anchorage-dependent and require expansion on solid surfaces. Here, we describe different approaches for the cultivation of Ver…

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