Search results for "high-throughput"

Article High-throughput process development and scale-up of an intermediate purification step for recombinant insulin
Introduction The ever-increasing need for higher throughput in process development has led to the introduction of new high-throughput process development (HTPD) tools. In purification development …

Article Optimizing Cation-Exchange Chromatography with High-Throughput Process Development for mAb Purification
This deeper level of understanding could be directly addressed by increasing the experimental space using high-throughput process development (HTPD). Leveraging the power of HTPD and DoE for chrom…

Article High-Throughput Process Development in an Historical Environment
Some of the remaining challenges in the upstream area were reported to be high-throughput metabolic analytics. On the subject of formulation, David Smithson from Genentech presented how the compan…

Article High-throughput screening methods to speed MAb process development
Add highly robust scale-up and the stage is set for shortening the time-to-clinic journey for MAbs High-throughput screening and optimization of a Protein A capture step in a monoclonal antibody p…

Article High-Throughput Process Development Handbook
Employing high-throughput tools for process development helps address these challenges. High-throughput process development (HTPD) shortens development time at the same time as it increases the am…

Article High-throughput screening and optimization of a multimodal polishing step in a monoclonal antibody purification process
The complexity of multimodal media requires a more thorough process optimization study in order to take full advantage of the outstanding potential of this technology. This calls for the development…

Article Report from the 2nd High-Throughput Process Development conference in Avignon, France
The 2nd International High-Throughput Process Development (HTPD) Conference took place June 4-7, 2012 in the historical location of Avignon, France. 117 participants from 19 countries met at the cla…

Article High-throughput screening and process development for capture of recombinant pro-insulin from E. coli
High-throughput screening quickly narrowed down the number of candidate chromatography media and suggested binding and elution conditions for further investigation. When capture step conditions were f…

Article High-throughput screening of HIC media in PreDictor™ plates for capturing recombinant Green Fluorescent Protein from E. coli
This study demonstrates a rapid, high-throughput process development workflow using parallel screening in 96-well plates to determine the most suitable HIC media and conditions for capturing recombina…

Poster High-Throughput Downstream Processing Using Cellulose Fiber Chromatography and ÄKTA™ Chromatography Systems
Developing a process or looking for a clone of interest often requires screening large numbers of samples. Many analyses require purified proteins, and often substantial hands-on time is required for …

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