Search results for " HTPD" in Posters

Poster New HTPD Conference is Coming. What Happened Last Time?
After the first two successful meetings in Krakow, Poland, in 2010, and Avignon, France, in 2012, the third HTPD meeting was in October 2014 held in yet another UNESCO World Heritage site - Siena, Ita…

Poster Automated HTPD technology for design of cleaning-in-place (CIP) protocols for chromatography resins
Cleaning-in-place (CIP) of chromatography media (resins) is instrumental for safe and cost efficient production of biopharmaceuticals. A cleaning procedure that efficiently removes impurities withou…

Poster Experimental investigation of scale effects in high throughput process development studies
In general, HTPD studies to develop chromatography steps can be performed using different miniaturized formats that support parallel experimentation. In this work we have analyzed effects related to l…

Poster To Speed Up the Process Optimization of the Described Biosimilar Product
When establishing purification processes for a biosimilar molecule it is important to develop steps that are scalable, selective and cost effective. This example describes a standardized workflo…

Poster Rapid Process Development of a CIEX Step for a Biosimilar
When establishing purification processes for a biosimilar molecule it is important to develop steps that are scalable, selective, and cost-effective. A cation exchange (CIEX) chromatographic ste…

Poster Accurate comparability assessment of a biosimilar interferon in process development
This application note describes how to achieve accurate comparability assessments using Biacore™ T200 and Amersham™ WB system in the development of a biosimilar. This is exemplified in this study…

Poster Influence of Chromatography Medium Sampling in Plate-based Benchmarking Studies
In this poster, influence of the physico-chemical properties of various media on preparation  of medium-containing microplates is discussed and examples are presented that show how  these properties…

Poster Evaluation of different cation multimodal ligand structures for capture of pro-insulin
The variation of ligand structures that can be attached to a base matrix is large. In this investigation 15 different cation multimodal ligands containing different hydrophobic and anionic groups we…

Poster Development of capture and intermediate chromatography steps for insulin purification
Resin screening and chromatography condition screening using an HTPD approach in a 96-well filter-plate format were performed. The results indicated that the media of choice for the capture step w…

Poster Comparison of Three Different Screening Techniques for Predicting Step Elution Conditions for a Cation Exchanger
Screening of chromatographic conditions can be done in several ways, such as 96-well plates, mini-columns, and tips. It is important that the screening can give an indication of the optimal conditio…

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