Search results for "mechanistic modelling" in Articles / App Notes
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Mechanistic Modeling of Preparative Ion-Exchange Chromatography
By Anurag Rathore, Vijesh Kumar
Among the various downstream processing unit operations that are used for purification of biotech products, chromatography is uniquely capable of providing resolu…
Article
Mechanistic Modeling: Does it Have a Future in Process Development?
The application of mechanistic models for process development and optimization has been a topic of discussion in the pharmaceutical industry for many years. Mechanistic models are considered as an a…
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Mechanistic Modeling: Current Advantages and Future Opportunities in Biopharmaceutical Process Development
Mechanistic modeling is considered a part of smart process development, which is a collection of approaches to get better process outcomes and speed up process development.
This week, Bioproce…
Article
Insider Recommendations for Getting Started with Mechanistic Modeling of Chromatography
Topics covered include:
0:45 - What is mechanistic modeling of chromatography?
3:47 - Obstacles to implementing mechanistic modelling.
5:10 - Top tips for implementing mechanistic modeling…
Article
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What is mechanistic modeling in chromatography?
Mechanistic models use computer simulations to decrease the number of experiments needed during process development. The simulatio…
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FAQ: Scale-up and scale-down with mechanistic modeling
A mechanistic model can simplify your process development projects. The model eases scale-up and scale-down between lab scale and production scale. To apply model-based scale-up and scale-down…
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Utilization of Mechanistic Modeling to Improve Process Development
To follow the QbD paradigm and keep up with shorter timelines, process developers are evaluating different approaches to improve process development workflows and gain a better process understanding…
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Mechanistic modeling quiz
Mechanistic models make it possible to create computer simulations of chromatograms. The simulations are based on physiochemical phenomena known to occur in chromatography. The benefit of a me…
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Advanced therapeutics process development using mechanistic modeling
Guterstam
Watch the interview of Peter Guterstam and Nick Whitelock (Cytiva), and learn about
the biological background of advanced therapeutics
what mechanistic modelling …
Article
How to put mechanistic modeling into practice
Make it happen! Learn about insider recommendations to get started with in silico process development.
Check out our resources on good modeling practice, case studies, and other publication…