Search results for " Axichrom" in Articles / App Notes
Article
Sanitization of AxiChrom™ Columns Packed with Chromatography Resin
This study evaluates sanitization methods based on 1 M sodium hydroxide (NaOH) as sanitization agent using methodology previously developed for peracetic acid (PAA).
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Article
Your Reliable Downstream Bioprocessing. Our Proven AxiChrom Columns
The goal for biopharmaceutical manufacturers is to develop a process that will deliver material for clinical trials quickly and smoothly, achieve success in these trials, and scale up to commercial …
Article
Efficient Sodium Hydroxide Sanitization with a Novel Procedure of AxiChrom™ Columns Packed with Chromatography Resin
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Sodium hydroxide (NaOH) cleaning-in-place is the widely accepted method of sanitization employed by biopharmaceutical manufacturers to avoid the excessive costs and delays of a…
Article
Video: The solution to smarter column packing
Åsa Bergström, Byeongchan Kim and Juhyeong Jo explain the benefits of AxiChrom™ process-scale columns.
Watch this video to learn more
Article
Fast Turnaround with Automated Column Packing
Traditionally, column packing has been an art rather than a science. The process can consume essential time and resources. Risking poor performance with a suboptimally packed bed is not an option. P…
Article
The use of Xcellerex™ mixing system as slurry tank when packing chromatography columns
In a related study, the XDM Quad Mixing System was evaluated for use with an AxiChrom™ 300 chromatography column. The mixer was used with the Intelligent Packing concept of AxiChrom columns for packin…
Article
Multidimensional Scale-Up of a Monoclonal Antibody Capture Step, Using ÄKTA™ pilot 600
The process, performed with MabSelect™ PrismA Protein A chromatography resin, was scaled up 20-fold from a 70 mL HiScale™ 26 column to a 1400 mL AxiChrom™ 100 column. Equivalent mAb recovery and purit…
Article
Process Chromatography Selection for Downstream Processing Applications
Earlier column packing was an art, today automatic packing solutions, such as the AxiChrom columns, are available and making this step much more reliable. Bioburden may occur and its origin varies. It…
Article
Technology solutions simplifying chromatography unit operations
Chromatography operations typically involve steps such as resin slurry preparation, column packing, cleaning, unpacking, and resin storage. While each of the aforementioned steps can potentially be …