Search results for " chromatography resin" in Articles / App Notes
Article
Process Chromatography: Continuous Optimization
Suppliers of chromatography resins are developing new resin chemistries and binding mechanisms to meet this need.
Several interaction modes
There are four major chromatographic techniques employed…
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Making the Move to Continuous Chromatography
“Data indicate that more than one column offers better efficiency, and greater yield of product per unit volume of chromatography resin per unit of time. That means that because the columns are smalle…
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Improving Process-Scale Chromatography
New resin chemistries
New chromatography resins and chromatography ligands are constantly being developed, according to Lotta Ljungqvist, head of bioprocess R&D for Cytiva. She points to several n…
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A Look at the Affinity Chromatography Landscape
The technology has also been used to develop chromatography resins for manufacturing of non-antibody biosimilars—such as FSH [follicle-stimulating hormone] and hCG [human chorionic gonadotropin]—and v…
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Process Chromatography Selection for Downstream Processing Applications
There is a continuous development of new chromatography resins combining separation modes. One example of this is the diffusion restricted Capto Core resin combining size exclusion with a functionaliz…
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Optimizing Resin Performance with Disposable Chromatography Solutions
Although the initial uptake of single-use chromatography solutions has been relatively slow, an increased need for higher-capacity resins and the demand for smaller batches has made disposable chrom…
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Innovative Chromatography Resins Can Improve Purity and Quality
Recent advances in chromatography resins can effectively impact the purification unit operation with positive consequences that reverberate both upstream to the bioreactor and downstream to filtration…
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Technology Innovations Improve Process Chromatography Performance
The development of pressure stable chromatography resins, which allows seamless scale-up with high linear velocities, was another innovation that helped the industry address past chromatography challe…
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Reducing Cross-Contamination Risks in Process Chromatography
Reducing Cross-Contamination Risks in Process Chromatography
Single-use systems provide replaceable fluid paths.
By Cynthia A. Challener
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Article
Development and Future of Protein A Chromatography Technology: Q&A with Jonathan Royce, Business Leader Chromatography Resins, Cytiva
What is your response to these concerns?
It is true that Protein A affinity chromatography resins have higher cost per liter compared to, for example, ion exchangers or HIC resins. It is also tru…