Search results for " fluid"

Article Fluid Handling in Biopharma Facilities
By Susan Haigney Contamination prevention in biopharmaceutical manufacturing is crucial, and the proper handling and storage of fluids is essential to limit the possibility of contamination. Facili…

Article Ready-to-use fluid management for inline conditioning (IC) large-scale chromatography systems
We used a selection of fluid management components from GE Healthcare Life Sciences ReadyToProcess platform of disposable and single-use equipment to arrange buffer and sample management solutions for…

Article Ready-to-use fluid management solutions for chromatography systems
A selection of fluid management components from GE Healthcare’s ReadyToProcess platform of disposable and single-use equipment was used to arrange buffer and sample management solutions for four typ…

Article Ready-to-use fluid management solutions for cross flow filtration systems
A selection of fluid management components from GE Healthcare’s ReadyToProcess platform of disposable and single-use equipment was used to arrange buffer and sample management solutions for two larg…

Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
For example, bicarbonates and some proteins in biological fluids, when in solution, tend to stabilize the hydrogen–ion concentration by neutralizing (within limits) both acids and bases so the solutio…

Article Best Practices in Qualification of Single-Use Systems
Because biomanufacturing may involve processing of fluids containing these chemical compounds, the chemical compatibility of single-use components with process fluids under process conditions should b…

Article Tools for Continuous Bioprocessing Development
Such high cell densities can be demanding for gas transport and fluid addition. In addition, removal with cell retention is a challenge. In fact, operation in continuous perfusion culture mode has not…

Article Modeling Bioreactor Performance
“Performance may be as much about the integration of the bioreactor in the overall biomanufacturing operation as it is about the physics of fluid dynamics. Analyzing with simulation scenarios, fluid p…

Article Challenging the cleanroom paradigm for biopharmaceutical manufacturing of bulk drug substances
The process fluid is often filtered for bioburden control within a controlled amount of time after completion of any open process step. Sanitization: To make sanitary by cleaning and disinfection,…

Article Challenges in Cell Harvesting Prompt Enhancements
Centrifugation challenges The centrifugation step uses the density difference between cells and the surrounding fluid, accelerating the separation and settling of cells. Industrial applications ty…

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