Search results for " sensors"
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Reconciling Sensor Communication Gaps
Process analytical technology (PAT), quality by design, and individual company- or process-centric quality initiatives are driving the development of bioprocess sensors and probes. Single-use systems …
Article
What’s New in Upstream Technologies
… suited to deliver the same standard of stability and performance as the company’s stainless-steel sensors (2).
The 550pH sensor is an electrochemical, fully disposable device with sensor stabili…
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Moving PAT from Concept to Reality
In-line sensors are placed in a process vessel or process stream to conduct the analysis in-situ. On-line sensors are connected to process side streams and perform periodic automatic sampling, returni…
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Real-Time Characterization of Biotherapeutics and Comparability of Biosimilars
In SPR imaging, the incidence angle remains fixed and the binding of biomolecules on a gold surface is measured as the change in reflectivity in relation to the incident ray intensity, unlike SPR sens…
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Single-use Bioreactors Have Reached the Big Time
Most common are pH, dissolved oxygen, and carbon dioxide sensors based on fluorescence technology. Others are gaining acceptances, such as capacitance. Newer technologies have more recently been intro…
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Achieving Process Balance with Perfusion Bioreactors
Equipment suppliers are responding to needs for more durable reactors and sensors, a greater variety of monitoring technologies, and bioreactors that can integrate with cell retention devices.
Per…
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Improving PAT for Biologics
Advances in high-throughput systems, Raman and near-infrared (NIR) spectroscopy, high-performance single-use sensors, and chemometric methods are also helping manufacturers of biopharmaceuticals overc…
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Improving Upstream Predictability
Some of the most significant gains have been made in cell line expression, advanced sensors, and automation, says Atul Mohindra, R&D director for biomanufacturing at Lonza Pharma and Biotech. “Using a…
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Automating Bioprocesses
For example, tubing sets typically are supplied gamma-irradiated by a third party, and sensors are typically pre-calibrated and gamma irradiated. All this additional information needs to be part of th…
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Digitalization: The Route to Biopharma 4.0
The equipment can be interfaced with the corresponding digital twins using sensors and actuators such that the real time data is fed to the digital twins and the in silico predicted can be employed fo…