Search results for "viral vectors"
Article
Register now: Viral Vector Production for Gene Therapy
In partnership with NIBRT, our eLearning course, “Viral Vector Production for Gene Therapy”, is available on the award winning NIBRT Online Academy.
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Article
Manufacturing of Vaccines and Viral Vectors
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With the pandemic outbreak of COVID-19, there is intense focus on developing a vaccine. However, the challenge not only lies in developing a vaccine but also i…
Webcast
Viral Vector Production for Gene Therapy (in partnership with NIBRT)
In partnership with NIBRT, our eLearning course, “Viral Vector Production for Gene Therapy”, is available on the award winning NIBRT Online Academy.
Article
Lentiviral Vector Upstream Process in Single-use Bioreactors
However, cost-effective manufacturing of lentiviral vectors at commercial scales has proven difficult and remains a pressing issue for the marketing of therapies that depend on their application.
Article
Production of Recombinant Adeno-associated Virus Vectors Using Microcarrier Culture of HEK293T Cells
As of March 2020, more than 4310 gene therapy clinical trials have been performed worldwide, with only 518 of them in Phase III and Phase IV. As the gene therapy projects enter clinical Phase III or g…
Article
Genetic Vaccine Platforms Demonstrate Their Potential
In a pandemic, genetic vaccines offer several advantages over traditional approaches.
By Cynthia A. Challener
For a vaccine to be effective, the components of the disease o…
Article
A Look at the Affinity Chromatography Landscape
…urification of not only novel protein-based biologics, but a wide range of other biomolecules, from viral vectors and nucleic acids to cells.
Beyond impurity removal for “simple” proteins
Aff…
Article
Emerging Therapies Test Existing Bioanalytical Methods
In addition, many of the viral vectors may react with antibodies already present in animals and humans. To prevent these pre-existing antibodies from interfering with the program, it is recommended to…
Article
Maximum Output Starts with Optimized Upstream Processing
Viral vectors are a special case
Viral vectors, which are used directly in therapeutics and vaccines and also in the production of gene and gene-modified cell therapies, represent a special case…
Article
Design Considerations for a Commercial Cell and Gene Therapy Facility
“We have to split this discussion into two parts for a successful comparison: first, viral vectors for gene therapy and second, cell and ex-vivo gene therapy,” remarks Senthil Ramaswamy, head of R&D, …