Search results for "bispecific"

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
One of these promising groups of antibodies is called bispecifics, where one antibody can simultaneously bind to two targets. Advanced antibody engineering has resulted in the ability to manufactu…

Article Bispecific Antibody Purification: Insights and Case Studies
Here are some industry insights to help you navigate the bispecific jungle. Read Article

Article Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
Learn more about bispecific purification

Poster Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
A single‑step downstream process using protein A chromatography to purify a bispecific antibody (BsAb) in early screening has been successfully developed to replace an existing‑three step proces…

Article Witnessing Major Growth in Next-Generation Antibodies
The global market for next-generation antibodies, including antibody drug conjugates (ADCs), engineered antibodies, bispecific antibodies, antibody fragments, antibody-like proteins and biosimilar ant…

Article A Look at the Affinity Chromatography Landscape
Affinity chromatography for bispecific antibodies Due to the molecular diversity of bispecific antibodies, a general purification platform is not available. A toolbox approach is needed, in which …

Article Advances in Engineering of Protein-Based APIs
Bi/multispecific proteins Bispecific antibodies are an important emerging area in advancing protein engineering for pharmaceutical products, and several bispecifics based on immunoglobulin scaffol…

Article Best Practices for Selecting a Top-Quality Cell Line
“A balanced plasmid ratio usually has dramatic impact on some formats of bispecific antibody cell line development to minimize impurities,” she explains. Factors such as cell growth and metabolism, as…

Article Platform for Purification of VHH-type Antibody Fragments
Click here to read this poster >> Protein A affinity chromatography resins have been used to purify monoclonal antibodies (mAbs) by the bioprocess industry at all scales for a long time. Howev…

Article The Challenge of Disruptive Technologies in Bioprocessing
The industry pipeline is growing in complexity to include emerging molecules such as bispecific antibodies, antibodydrug conjugates (ADCs), and those viral vectors for gene and cell therapies. Some of…

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