Search results for "buffer"
Improving mAb Manufacturing Productivity by Optimizing Buffer and Media Prep Process Flow
Buffers and salts are typically the largest constituents by volume used in the downstream processing steps for manufacturing most biopharmaceutical products. A typical monoclonal antibody (mAb) proces…
Virus purification using superheated buffer in place (SBIP) for packed bed chromatography
Superheating occurs when pressurized liquids are heated above their normal boiling temperature; water-based buffer systems can be heated to well above 121°C, the temperature normally regarded as the s…
Will My Buffers Work When Using an Inline Conditioning System?
In-line preparation of buffers from highly concentrated, single-component stock solutions saves both time and storage space. Compared with preparing one concentrate per buffer formulation, many differ…
Make buffer preparation more time and cost efficient with inline conditioning
Preparation of these buffers is a challenge that in-line conditioning can overcome. Inline conditioning simplifies buffer preparation and offers significant reduction in number of tanks, buffer soluti…
Automated In-Line Buffer Preparation from Ready-Made Stock Solutions in a mAb Process Step
This application note describes a lean approach to buffer preparation by implementing in-line conditioning (IC). Buffers of different formulations for a mAb chromatography capture step were prepared i…
Overcoming Buffer Challenges With In-Line Conditioning
In this application note, we show how in-line conditioning (IC) can help reduce the number of hold tanks and floor space needed for buffer preparation and storage. With IC, buffers of desired formulat…
Buffer Management Solutions for Large-Scale Biomanufacturing
This article discusses solutions such as inline conditioning, outsourcing buffer preparation, and more. Click here to read more >>
Automated Buffer Preparation – Increasing Production Capacity While Maintaining Footprint
In fact, buffer preparation is known to be one of the most resource-intensive activities in biomanufacturing, as large volumes of buffers and process liquids are often required as production capacity …
Can You Trust a Machine for Downstream Bioprocess Buffer Preparation?
Still, resource-intensive buffer preparation has received little attention in biomanufacturing. Some of the questions to be answered are: - Can automated buffer management solutions save resour…
Buffer plate preparation using ÄKTA™ avant system and BufferPro tool
A method was developed for automatic buffer preparation of 48-well buffer plates using ÄKTA avant chromatography system and the BufferPro tool in UNICORN™ 6 software.Using BufferPro with ÄKT…