Search results for " Virus-like particles"

Article Virus-like Particles as Therapeutic Moieties of the Future
Analytical and functional characterization of virus-like particles enables process reproducibility and product consistency. By Ramesh Kumar, Manidipa Banerjee, Anurag S. Rathore Virus-like…

Article Removal of DNA and baculovirus from influenza virus-like particles using Capto™ Q
This application note presents a chromatographic step for efficient removal of DNA and baculovirus (BV) from influenza virus-like particle (VLP) supernatant solutions, manufactured using Novavax Inc…

Article Bioterminology: A Guide to the Biopharmaceutical Lexicon
Bioterminology: A Guide to the Biopharmaceutical Lexicon This lexicon was generated by the editors of BioPharm International magazine. Please feel free to email your suggestions for terms that s…

Article Ensuring Viral Safety of Viral Vaccines and Vectors
Ensuring Viral Safety of Viral Vaccines and Vectors Viral vaccines and viral vectors used in biotherapeutic applications carry the risk of microbial contamination, which must be addressed. …

Article Novel Vaccine Technologies Meet the Need for Pandemic and Therapeutic Solutions
Two different types of immunogenic particles are used: virus-like particles (VLPs) and recombinant protein micelles. Novavax’ seasonal and pandemic influenza vaccines consist of VLPs or recombinant pa…

Article A Look at the Affinity Chromatography Landscape
Another option is the use of monolithic, convective chromatography supports, which are widely used for the purification of macromolecules such as viruses, virus-like particles, plasmid DNA, and cells.…

Article SEC in the Modern Downstream Purification Process
In general, virus and virus-like particles are ideally suited to SEC. Governmental pressures to localize vaccine manufacturing in the country of origin also make SEC applications more attractive. The …

Article Generating a Fully Processed Antibody
The authors outline cell-line development and process scale-up for an antibody program in which the antibody requires additional processing by a site-specific enzyme for correct functionality. B…

Article Updating Viral Clearance for New Biologic Modalities
Secondly, the quantity of virus or virus-like particles in these different cell lines may potentially be quite high, he says, requiring multiple efficient virus-removal steps to deliver the clearance …

Article High-Throughput Process Development in an Historical Environment
Presentations, discussions, and information-sharing on modern bioprocess technology and high-throughput process development (HTPD) in an historical and culturally enriched environment is the essence…