Search results for "Protein A" in Posters

Poster Guidelines for protein purification at low temperature
The main reason for performing protein purification at low temperature is to preserve the integrity of proteins and whole samples during the process. Working at lower temperature reduces proteolytic…

Poster Protein Purification Methods
Living organisms are enormously complex. Proteins are fundamental for executing a wide variety of life controlling functions. Proteins are of high interest both in the academic community as we…

Poster A Next Generation Protein A Chromatography Resin for Improved Productivity and Bioburden Control
• The increased upstream titers in mAb production seen in recent years may make the Protein A capture step a bottleneck.  • Protein A columns columns are also more prone to bioburden contamination…

Poster Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
MabSelect™ PrismA protein A resin was selected for the capture step. Most fragments could be removed as early as the capture step using gradient elution from pH 5 to 3.5, without the need for addition…

Poster Setting new standards for cleaning and sanitization of Protein A chromatography resins
Finally, the functionality and lifetime of the protein A resins after regular exposure to cleaning and sanitization agents were measured by confocal microscopy and conventional chromatographic methods…

Poster Biphasic cultivation strategy for optimized protein expression
In biphasic cultivations, the culture conditions are changed to allow maximum recombinant protein expression after accumulating biomass during an initial phase.  In this study, a biphasic cultivation …

Poster Host Cell Proteins beyond ELISA with label free interaction and imaging technologies
Traditional Host Cell Protein (HCP) ELISA assays depend on the quality of the assay antibodies and provide overall HCP population data only. However, the levels of individual HCP may be independentl…

Poster Process Economy Impact of Protein A Resin Alkaline Stability
This poster presents a process economy simulation comparing three protein A chromatography resins with the aim to demonstrate the influence of dynamic binding capacity (DBC) and alkaline-stability of …

Poster Impact of sporicidal agent on MabSelect SuRe™ protein A resin lifetime
In this application note, the effects of treating MabSelect SuRe protein A affinity  resin with 20 mM PAA every fourth process cycle for more than 100 cycles were investigated. The results show that t…

Poster Evaluation of Protein A resin lifetime during extensive use (overloading) in continuous chromatography mode
This application note compares the performance of MabSelect SuRe pcc resin designed for continuous capture of mAbs, with the conventional high-capacity Protein A resin MabSelect SuRe LX. The study was…

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