Search results for " process modeling"

Article How to put mechanistic modeling into practice
Make it happen! Learn about insider recommendations to get started with in silico process development. Check out our resources on good modeling practice, case studies, and other publication…

Article Good modeling practice: workflow and case study
Learn more about a recommended mechanistic modeling workflow for successful in silico chromatography process development. The workflow is illustrated with examples from a modeling case study a…

Article Benefits of DoE vs mechanistic modeling
Hear about the main differences between mechanistic modeling and design of experiments when used during chromatography process development. You will learn that, quite often, these methods work…

Article Adsorption isotherm models for chromatography
Read on commonly used models for the thermodynamics of adsorption within a chromatography column. Indeed, in order to create a complete chromatography model, the adsorption of compon…

Article Mechanistic modeling quiz
Mechanistic models make it possible to create computer simulations of chromatograms. The simulations are based on physiochemical phenomena known to occur in chromatography. The benefit of a me…

Multimedia Using mechanistic modeling in process development for advanced therapeutics
Peter Guterstam and Nick Whitelock discuss mechanistic modeling in process developemnt of advanced therapeutics. MORE Q&As WITH INDUSTRY LEADERS >>

Article Scale-Up Model of a mAb Process from Microbioreactor to XDR-1000
READ ARTICLE >> In process development, it is desirable to test process parameters in small scale and later scale up the process into larger production scale. A theoretical scale-up study was per…

Article Do Modeling and Simulation Tools Really Benefit the Biosimilar Industry?
The business impact of modeling and simulation tools is not well understood and requires clarification of their benefits to drug development. READ THE FULL ARTICLE >>…

Article Engage a mechanistic modeling expert – or become one
The application of mechanistic modeling requires expertise for effective use. When planning to implement this ground-breaking technology one essential question must be addressed befor…

Article Mechanistic chromatography modeling in practice
Access insider recommendations for getting started with mechanistic modeling of chromatography, but also case studies and scientific publications. ACCESS THE RESOURCE HUB >>…

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