Search results for " antibodies"

Article Witnessing Major Growth in Next-Generation Antibodies
Challener Next-generation antibodies are designed to be more specific and are often more potent than traditional monoclonal antibodies (mAbs). As a result, their commercial potential is significan…

Article Antibody Production in Microbial Hosts
Rathore, Jyoti Batra The biopharmaceutical industry is growing exponentially, driven by an ever-increasing demand for monoclonal antibodies (mAbs) and related products that are capable of treating…

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
By Robert Karlsson Abstract Biotherapeutic antibodies are still the largest growing class of medicines and are used globally to treat a wide range of diseases such as cancer, asthma, and rheum…

Article Advances in Linker Technology: Improving the Safety and Efficacy of Antibody Drug Conjugates
“ADCs can, through the linkage of cytotoxic drugs to antibodies, safely deliver cytotoxic drugs that cannot be administered systemically because they are only released at the site of action, and it is…

Article Single-Domain Antibodies for Brain Targeting
Smaller recombinant antibody fragments as single-domain antibodies (sdAbs) are emerging as credible alternatives because of their target specificity, high affinity, and cost-effective recombinant prod…

Article Generating a Fully Processed Antibody
Expression of tagged antibodies in the FGE clonal cell line The selected FGE line was used as the base cell line to express two different antibodies. The two antibodies bind to different targets w…

Article HT Multi-Product Liquid Chromatography for Characterization of Monoclonal Antibodies
ABSTRACT Monoclonal antibodies represent a significant portion of sales in the biopharmaceuticals market. Ever-growing biotechnology pipelines have greatly increased demand for higher throughput, …

Article The Development and Application of a Monoclonal Antibody Purification Platform
The following article describes the development of a purification platform for monoclonal antibodies (MAbs) at Pfizer's Global Biologics division, including how the individual unit operations have bee…

Article Economic drivers and trade-offs in antibody purification processes
The success of therapeutic monoclonal antibodies (MAbs) in the treatment of indications such as cancer and autoimmune diseases has fuelled clinical trial activities; in recent years MAbs have become t…

Article Purification Strategies to Process 5 g/L Titers of Monoclonal Antibodies
Over the past five years, there has been a dramatic increase in the titers of recombinant proteins, particularly in the production of IgG monoclonal antibodies (MAbs) using Chinese hamster ovary (CHO)…

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