Search results for "perfusion"

Article Achieving Process Balance with Perfusion Bioreactors
With rising pressure to reduce costs and streamline bioprocess development, biopharmaceutical manufacturers are exploring the application of perfusion to a wider selection of biomolecules. “Perfus…

Article Perfusion in the 21st Century
Now, improved continuous culture technologies such as perfusion are on the rise, as biosimilar manufacturers look for new ways to cut costs while increasing quality and productivity. With perfusio…

Article Highly efficient inoculum propagation in perfusion culture using WAVE Bioreactor™ systems
Fed-batch cultures were inoculated with cells propagated in either batch or perfusion cultures. All cultures were grown in disposable Cellbag™ bioreactors using the WAVE Bioreactor system. Cell concen…

Article Perfusion Culture Using TFF or ATF as Cell Retention Method
Compared with batch or fed-batch processes, perfusion processes also allow cells to be maintained in exponential growth phase for an extended period of time and reach higher viable cell densities. …

Poster Repurposing Fed-Batch Media and Feeds for Highly Productive CHO Cell Perfusion Processes
Here, they show that they can obtain culture media that successfully support perfusion cultures in bioreactors at cell-specific perfusion rates (CSPR) below 25 pL/cell/day. High productivities and fav…

Webcast Development Strategies for High-Performing Perfusion Media
In this webinar, an expert describes a structured approach for developing a perfusion medium from a combination of commercially available medium and feeds. Learn how this methodology can be applied to…

Poster Efficient approaches for perfusion medium development
This study presents two approaches for the development of a high-performing perfusion medium from a commercially available platform comprising medium and feeds.

Poster An intensified perfusion one-step seed process with high-density cell banks
This work describes how the use of perfusion in the seed culture expansion process, in combination with the use of high-density cell banks, drastically can reduce processing time, simplify operation…

Resource Development Strategies for High-Performing Perfusion Media
Webinar, March 24, 2015

Article Tools for Continuous Bioprocessing Development
However, continuous culture operation, in all its forms--chemostat, turbidostat, and perfusion--can support metabolic flux analysis for increased process understanding (see sidebar). Continuous perfus…

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