Search results for " bispecific antibodies"

Article Witnessing Major Growth in Next-Generation Antibodies
The global market for next-generation antibodies, including antibody drug conjugates (ADCs), engineered antibodies, bispecific antibodies, antibody fragments, antibody-like proteins and biosimilar ant…

Article Applications of Surface Plasmon Resonance for Detection of Bispecific Antibody Activity
Advanced antibody engineering has resulted in the ability to manufacture new recombinant bispecific antibodies suitable for therapeutic use. FDA has approved a bispecific antibody—Amgen’s Blincyto (bl…

Article Single-Domain Antibodies for Brain Targeting
Single-domain antibodies are emerging as credible alternatives due to their target specificity, high affinity, and cost-effective recombinant production. Smaller recombinant antibody fragments a…

Article Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
A single-step downstream process using protein A chromatography to purify a bispecific antibody (BsAb) in early screening has been successfully developed to replace an existing three-step process. T…

Article Bispecific Antibody Purification: Insights and Case Studies
New modalities, like bispecific antibodies, present unique challenges compared to mAb production. For purification, there’s not just one right answer to which strategy to use. Here are some industry…

Poster Single-Step, Protein A Chromatography Process for Bispecific Antibodies in Early Screening
A single‑step downstream process using protein A chromatography to purify a bispecific antibody (BsAb) in early screening has been successfully developed to replace an existing‑three step proces…

Poster Development of a Purification Platform Process For a Unique Next-Gen Antibody
Various bispecific antibody formats have been developed over the past decade.  NovImmune's novel bispecific antibody format, the κλ-body, has a molecular structure similar to standard monoclonal antob…

Article Platform for Purification of VHH-type Antibody Fragments
Click here to read this poster >> Protein A affinity chromatography resins have been used to purify monoclonal antibodies (mAbs) by the bioprocess industry at all scales for a long time. Howev…

Article A Look at the Affinity Chromatography Landscape
Affinity chromatography for bispecific antibodies Due to the molecular diversity of bispecific antibodies, a general purification platform is not available. A toolbox approach is needed, in which …

Article Advances in Engineering of Protein-Based APIs
Advances in Engineering of Protein-Based APIs New platform technologies, advanced modeling tools, and addressing patient needs are important developments. By Cynthia A. Challener …

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